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UEU » Journal » Fisioterapi Posted by [email protected] at 04/08/2021 13:56:01 • 979 Views
CONTINUOUS ENVIRONMENTAL ENRICHMENT AND AEROBIC EXERCISE IMPROVES SPATIAL MEMORY: FOCUS ON RAT HIPPOCAMPAL BDNF AND NGFPengayaan lingkungan terus menerus dan latihan aerobik meningkatkan memori spasial: fokus pada BDNF dan NGF hippocampal tikusCreated by :
D.I.I. Santoso ( None ) S. Yolanda1; S. Redjeki; T. Andraini; K. Ivanali
Subject: | LINGKUNGAN MEMORI LATIHAN | Alt. Subject : | ENVIRONMENT MEMORY EXERCISE | Keyword: | environmental enrichment aerobic exercise BDNF NGF spatial memory |
Description:
Memory is an important cognitive function in humans. Exercise and environmental enrichment (EE) exposure have
positive effects on memory function via improved neurogenesis through expression of growth factors such as brainderived
neurotrophic factor (BDNF) and nerve growth factor (NGF). Exercise and environmental enrichment have
independently been shown to increase BDNF and NGF, but the effect of the combination of these treatments has
not been widely studied. This experimental study aims to analyse the effect of aerobic exercise, EE exposure, and
combination of aerobic exercise and EE exposure on memory function. This study used twenty 7-month old male
Wistar rats that were given treatment for 8 weeks. Memory function was tested using forced alternation Y-maze.
Hippocampal expression of BDNF and NGF were also assessed. The results showed the combination group has
highest performance in memory function test and also the highest level of hippocampal BDNF and NGF (P<0.05).
It can be concluded that the combination of aerobic exercise and continuous EE exposure produces the best results
for memory function through higher levels of hippocampal BDNF and NGF in adult rats.
Date Create | : | 04/08/2021 | Type | : | Text | Format | : | pdf | Language | : | Indonesian | Identifier | : | UEU-Journal-11_1809 | Collection ID | : | 11_1809 |
Source : Comparative Exercise Physiology, 2020; 16 (2): 121-128
Relation Collection: Fakultas Fisioterapi
Coverage : Civitas Akademika Universitas Esa Unggul
Rights : @2021 Perpustakaan Universitas Esa Unggul
Publication URL : https://digilib.esaunggul.ac.id/continuous-environmental-enrichment-and-aerobic-exercise-improves-spatial-memory-focus-on-rat-hippocampal-bdnf-and-ngf-21045.html
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- CONTINUOUS ENVIRONMENTAL ENRICHMENT AND AEROBIC EXERCISE IMPROVES SPATIAL MEMORY: FOCUS ON RAT HIPPOCAMPAL BDNF AND NGF
https://www.wageningenacademic.com/doi/abs/10.3920/CEP190036
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